Cognitive decline preceding the onset of psychosis in patients with 22q11.2 deletion syndrome

By Wai Lun Alan Fung (with others, see publication link for more information)
View profile for: Dr. W.L. Alan Fung

Importance: Patients with 22q11.2 deletion syndrome (22q11DS) have an elevated (25%) risk of developing schizophrenia. Recent reports have suggested that a subgroup of children with 22q11DS display a substantial decline in cognitive abilities starting at a young age.

Objective: To determine whether early cognitive decline is associated with risk of psychotic disorder in 22q11DS.

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This is a peer reviewed Article

Article in JAMA Psychiatry
Volume #: 72
Issue #: 4
Pages: 377-385
Year: 2015

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